The Digidata^® 1550B is the latest high-resolution, very low-noise digital-to-analog/digital-to-analog converter developed by MD, USA. Its biggest feature is that the built-in noise remover can remove four channels of noise at the same time. Axon Digidata 1550B is designed for electrophysiological experiments and has a wide range of applications, including single-channel recording, large-diaphragm recording, whole-cell recording, traditional intracellular recording, extracellular field potential recording, and artificial bilayer patch clamp recording.

· Main feature

High resolution, low noise

The perfect data acquisition system, high resolution, low noise, high sample rate, and low digital noise are perfectly represented on this DAC. Each input path is processed using a separate analog-to-digital converter, which suppresses crosstalk between the input channels.

Fig. 1 Patch clamp single channel recording on ex vivo HEK293 cells transfected with olfactory loop nucleotide-gated channel alpha subunits. At 2 μM cGMP concentration, the membrane fixed voltage is +60 mV.
Fig. 2 Excitatory postsynaptic currents evoked on cortical striatum neurons cultured in brain sections. The stimulating electrode was placed in the V/VI cell layer of the cortex and the membrane fixed voltage was -70 mV.
Fig. 3 Action potentials of neurons recorded in dorsal root ganglion isolated from rat brain tissue. The stimulation current evoked by the action potential was 110 μA, and the membrane resting potential was -50 mV.

· Four-channel noise removal
Built-in noise remover removes 50/60Hz AC noise from four channels at the same time.

· Short denoising time
Removes 50/60Hz AC noise in 1 second without affecting 50/60Hz bandwidth signal acquisition.

· Easy to set up
Simply complete the installation software and connect it to a desktop or laptop via USB. Connect one end of the power cord to the power supply and the other end to the rear AC power input connector. All signal input and output connections can then pass through. The interface on the front panel is completed.

· High performance software
The included PClamp 10.6 software can record experimental data. The software is perfectly compatible with the Windows operating system. PClamp 10.6 software is a data acquisition program that supports continuous (uninterrupted) event monitoring and provides operational oscilloscope mode, and supports dye fluorescence PMT ratio detection. Perform offline benchmark display tests and display data in a spreadsheet format. PClamp 10.6 software records in ABF binary data format, optionally exporting data in ASCII text format.

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