Features and Benefits
• Langendorff and Optional Working Heart Perfusion in a Single System
• Compact Design, Optimized Individually for: Mouse, Rat or Guinea Pig
• Constant Pressure or Constant Flow Perfusion in one unit, easily switch between the two modes
• Compact, doesn’t require wall-installed high water columns, suitable for hearts from hypertensive rats
(perfusion pressures up to 300 mmHg are possible)
• Unique integrated small volume Aortic Block with built-in Bubble Trap and Windkessel
• Large Fully-Heated Heart Chamber
– Natural physiological environment for the isolated heart
– Hearts are kept alive for hours in a very stable physiologic environment
– Easy-to-use with smooth open and closed operation
– All electrodes, catheters and probes are fully
enclosed for easy access and to maintain physiological conditions while performing the experiments
• Unique cannula design
– Cannula resistance is optimized according to Hagen-Poiseuilles physical law
– Different cannula sizes available, all metal, no fragile glass cannulae
• Proprietary Mini Holders allow easy and stress-free positioning of electrodes, catheters and probes

Applications
• Treatment with Inotropic Substances
• Cardiac Rhythm
• Ischemia and Reperfusion
• Cardiac Preconditioning
• Cardiovascular Screening Performance
• Phenotyping of Transgenic Animals
• Compound Screening

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